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. 2012 Jan;19(1):11–16. doi: 10.1128/CVI.05376-11

Fig 1.

Fig 1

Immune responses to PA-adjuvant vaccine formulations. PA-specific IgG endpoint titers (A and D) and LTx neutralizing antibody titers (ED50) (B and E) were determined by ELISA and toxin neutralization assay, respectively, in individual serum samples of rabbits immunized with PA+HLT by the TCI route (A and B) or with PA-adjuvant vaccine formulations by the i.m. route on weeks 0, 4, and 8 (D and E). Data represent means ± standard errors of the means. Kaplan-Meier survival curves for rabbits challenged with 100 LD50 Ames strain spores on week 14 (C) or 19 (F) of the study are shown. ∗, P ≤ 0. 0.01.