PRNT and ELISPOT-MNT in Vero E6 cells. These data represent the extent of plaque reduction compared to a virus dose control as a function of the concentration of various MAbs that show cross-reaction toward four DENV serotypes. A1, B1, and C1 were measured by PRNT, while A2, B2, and C2 were assayed by ELISPOT-MNT.