Table 1.

Specificity of MAbs^a

Immunogen	MAb	Isotype	Indirect ELISA of EDIII result				IFA result
			DENV-1	DENV-2	DENV-3	DENV-4	DENV-1	DENV-2	DENV-3	DENV-4
DENV-1 EDIII	5E7A6	IgG1	+	+	+	+	+	+	+	+
DENV-1 EDIII	5A12A7	IgG1	+	+	+	+	+	+	+	+
DENV-2 EDIII	4C58A2	IgG1	+	+	+	+	+	+	+	+
DENV-3 EDIII	2D73A7	IgG1	−	−	+	−	+	+	+	+
DENV-3 EDIII	4A19A2A33	IgG1	+	+	+	+	+	+	+	+
DENV-3 EDIII	2D13A12	IgG2b	+	+	+	+	+	+	+	+
DENV-4 EDIII	1E1A7	IgG1	+	+	+	+	+	+	+	+
DENV-1-4 EDIII	3E31A4	IgG1	+	+	+	+	+	+	+	+
DENV-1-4 EDIII	5E56A5	IgG1	+	−	+	+	+	+	+	+
DENV-1-4 EDIII	2B11A35	IgG1	+	−	+	−	+	+	+	+

^aThe reactivity of each MAb was determined using indirect immunofluorescence assay (IFA) on C6/36 cells infected with DENV and indirect ELISA of EDIII using recombinant EDIII protein from the four DENV serotypes.