Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Role of APOBEC deaminases in occult HBV infection. (A) Deamination activity of APOBEC protein converts cytosine to uracil in the HBV genome, leading to various mutations associated with occult HBV infection. (B) Deamination-independent activity of APOBEC deaminases inhibits DNA-RNA hybrid formation, increases susceptibility to nuclease digestion, and decreases protein processing, eventually leading to occult HBV.
