Table 2.
Tobramycin MIC (mg/liter) | Target attainment (% of 9,999 simulated subjects) |
---|---|
0.25 | 100 |
0.5 | 100 |
1.0 | 70 |
2.0 | <1 |
4.0 | 0 |
Cefepime and tobramycin were administered at doses of 2 g every 8 h and 7 mg/kg/day, respectively. The rates of cefepime's target attainment for the 2-g-every-8-h dose are 100% at an MIC of 4 mg/liter and 99.5% at an MIC of 8 mg/liter.