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Antiviral activity of F18 based on time of addition, compared with that of other ARVs. The antiviral activity of F18 was measured at different times following addition of the compound in order to determine the stage in the HIV-1 replication cycle at which F18 inhibits. The ARV inhibitors NVP, AZT, RTV, RAL, and TAK-779 were used in parallel as controls.
