PFGE analysis of XbaI-digested genomic DNAs of Tetr strains. Lanes: 1, 15, 16, and 30, Lambda PFGE marker (New England Biolabs); 2,14, 17, and 29, Low Range PFGE marker (New England Biolabs); 3 and 18, E. coli 177pMG252; 4 and 19, E. coli 43pMG298; 5 to 10, Tetr E. coli isolates obtained before treatment; 11, 12, 13, and 18, Tetr isolates obtained during treatment; 20 to 28, Tetr isolates obtained after treatment. Isolates whose patterns are shown in lanes 5, 6, 7, 8, 9, 11, 20, 22, 23, 24, 25, and 28 belong to phylogenetic group B1; those whose patterns are shown in lanes 10, 12, 13, 21, 26, and 27 belong to phylogenetic group D and have profiles similar to each other.