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Spin-state dependency of parameters of econazole binding with CYP164A2
| Buffer | Low-spin component (%) | Kd for econazole (μM) | Hill plot slope (SD) |
|---|---|---|---|
| HS | <5 | 0.098 (±0.016) | 2.34 (±0.05) |
| LS | ∼100 | 338 (±17) | 1.01 (±0.04) |
| Control | 66 | 1.07 (±0.15) | 1.41 (±0.09) |
| CB1 | 17 | 0.37 (±0.10) | 1.79 (±0.11) |
| CB2 | 34 | 4.05 (±0.56) | 1.04 (±0.04) |
