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Distribution of gyrA mutations among 97 fluoroquinolone-resistant H. pylori isolates
| gyrA-encoded amino acid (nucleotide) mutation | No. (%) of isolates | MIC50/MIC90 (range) [mg/liter] |
|---|---|---|
| T87I (C260T) | 23 (23.7) | 16/16 (4–32) |
| N87K (C261A) | 26 (26.8) | 8/16 (4–32) |
| N87K (C261G) | 6 (6.2) | 4/16 (2–32) |
| A88P (G262C) | 1 (1.0) | 2 |
| D91N (G271A) | 30 (30.9) | 8/8 (2–32) |
| D91G (A272G) | 7 (7.2) | 8/8 (1,5–16) |
| D91Y (G271T) | 6 (6.2) | 4/8 (2–16) |
| D91H (G271C) | 1 (1.0) | 16 |
| None | 1 (1.0) | 8 |
