Fig 1.

Major structural features of plasmid pOXA-48a from K. pneumoniae 11978 (22) in comparison with the IncL/M plasmids pCTX-M-3 (11) and pNDM-HK (14). White boxes indicate plasmid scaffold regions that are in common among plasmids. The locus Tra within the box is indicated. Resistance genes are indicated by orange boxes, except the β-lactamase genes, which are indicated by blue boxes. Transposon-related genes (tnpA, tnpR, and tnpM) and insertion sequences are indicated by red boxes. Replicase genes are indicated by purple boxes.