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. Author manuscript; available in PMC: 2013 Jan 3.
Published in final edited form as: Circulation. 2011 Nov 15;125(1):100–112. doi: 10.1161/CIRCULATIONAHA.111.042598

Figure 7.

Figure 7

Direct and indirect contributions of allogeneic CDCs to myocardial repair. Rare events of long-term engraftment and cardiogenic (A,B) or angiogenic (C) differentiation of allogeneic CDCs could be detected. More importantly, syngeneic and allogeneic CDCs promoted endogenous mechanisms of regeneration by stimulating cardiomyocyte cycling (D,E,G,H) (n=5–8/group at each timepoint), host stem cell recruitment (F,I) (n=5–8/group at each timepoint) and angiogenesis (J,K) (n=8/group). (* p<0.05 vs syngeneic, allogeneic groups; arrows in D,E denote cardiomyocyte nuclei, while arrowheads denote non-cardiomyocyte nuclei; arrows in F denote c-Kit+ cells; A–F scale bars: 20 μm; J,K scale bars: 100 μm)