Table 1. Characterization of the chimeric immune system.

	Blood	Bone marrow	Spleen
% hCD45/total CD45	22.6±2.1	29.6±3.2	12.8±0.9
Monocytes
% total hMono/hCD45	15.1±2.2	7.4±0.7
% CD14high hMono/hCD45	8.7±1.7
% CD14low hMono/hCD45	6.3±2.7
% CD11b+CD14−/hCD45			12.0±1.6
% CD11b+CD14+/hCD45			20.8±2.6
Granulocytes
% total hGranulo/hCD45	15.4±2.1
% hCD66b+neutrophil/hCD45	8.75±1.95
% CD16+ neutrophil/hCD45	11.4±1.9
% hCD15+ neutrophil/hCD45	10.8±2.1	3.8±0.4
% hGranulo/total Granulo	33.0±3.9
Myeloid cells
% CD11b+/hCD45		47.1±5.2
% CD11b−/hCD45		52.9±5.2
NK cells
% hNK cells/hCD45	2.2±0.4
%hCD56+ hNK cells/hCD45			3.3±0.7
T lymphocytes
% hCD3/hCD45	0.34±0.10		1.9±0.3
B lymphocytes
% hCD19+/hCD45	57.1±3.9		65.4±2.5

Blood, bone marrow and splenic digests were analysed by flow cytometry to define the leukocyte populations (n = 26 mice). Treatment groups were matched by degree of peripheral blood chimerism prior to IgG injection. hMono = human monocytes. There was no significant difference in degree of chimerism or human granulocyte reconstitution between the experimental groups.