Table 3. Risk of one-month and one-year all-cause mortality according to the four frailty instruments in hospitalized older patients.
| Follow-up | Frailty index | HR | 95% CI | p-value** |
| FI-SOF-1 | 1.00 | |||
| FI-SOF-2 | 1.87 | 1.27–2.76 | 0.0016 | |
| FI-SOF-3 | 2.42 | 1.16–5.04 | 0.0184 | |
| FI-CD* | 1.13 | 1.10–1.16 | <0.0001 | |
| FI-CGA-1 | 1.00 | |||
| 1-month follow-up | FI-CGA-2 | 2.92 | 1.84–4.64 | <0.0001 |
| FI-CGA-3 | 4.54 | 1.68–12.24 | 0.0028 | |
| MPI-1 | 1.00 | |||
| MPI-2 | 2.05 | 1.40–3.00 | 0.0002 | |
| MPI-3 | 7.70 | 5.73–10.34 | <0.0001 | |
| FI-SOF-1 | 1.00 | |||
| FI-SOF-2 | 1.67 | 1.29–2.17 | <0.0001 | |
| FI-SOF-3 | 2.45 | 1.44–4.18 | <0.001 | |
| FI-CD* | 1.11 | 1.09–1.13 | <0.0001 | |
| FI-CGA-1 | 1.00 | |||
| 1-year follow-up | FI-CGA-2 | 2.93 | 2.25–3.83 | <0.0001 |
| FI-CGA-3 | 4.18 | 2.10–8.34 | <0.0001 | |
| MPI-1 | 1.00 | |||
| MPI-2 | 2.00 | 1.64–2.45 | <0.0001 | |
| MPI-3 | 5.70 | 4.49–7.22 | <0.0001 |
*continuous variables.
**p-values obtained fitting univariate proportional hazard regression models, accounting for clustering due to centre effect.
HR: hazard ratio; CI: confidence intervals; FI-SOF: Frailty Index derived from the Study of Osteoporotic Fractures; FI-CD: Frailty Index based on cumulative deficits; FI-CGA: Frailty Index based on a Comprehensive Geriatric Assessment; MPI: Multidimensional Prognostic Index.