Table 2. Factor Xa generation outputs for healthy controls (no known DVT).
| N | MaxR,pM/smean (SD) | TMaxR,smean (SD) | MaxL,nMmean (SD) | TMaxL,smean (SD) | AUCµM * smean (SD) | |
| Whole population | 473 | 8.0 (3.5) | 636 (31) | 5.8 (2.5) | 1737 (203) | 15.5 (6.7) |
| Sex | ||||||
| Men | 201 | 7.2 (2.8)† | 647 (29)† | 5.3 (2.1)† | 1769 (178)† | 14.2 (5.7)† |
| Women | 272 | 8.5 (3.9) | 629 (30) | 6.2 (2.7) | 1714 (216) | 16.3 (7.2) |
| Females without OC | 90 | 7.2 (2.3)† | 633 (27)† | 5.2 (1.7)† | 1677 (153) | 13.7 (4.7)† |
| Females with OC | 47 | 12.0 (5.4) | 601 (27) | 8.4 (3.5) | 1630 (198) | 22.2 (9.4) |
| Age (yrs) | ||||||
| ≤45 | 223 | 7.9 (3.9) | 633 (33)‡ | 5.7 (2.7) | 1678 (158)† | 15.0 (7.2) |
| >45 | 250 | 8.0 (3.1) | 639 (28) | 5.9 (2.2) | 1790 (223) | 15.9 (6.1) |
| BMI kg/m2 | ||||||
| ≤26 | 264 | 7.5 (3.4)† | 638 (32) | 5.4 (2.2)† | 1699 (173)† | 14.2 (6.0)† |
| >26 | 193 | 8.6 (3.6) | 633 (29) | 6.4 (2.6) | 1789 (227) | 17.2 (7.1) |
N: population size; BMI: Body Mass Index, OC: oral contraceptives, MaxR: maximum rate, TMaxR: time to maximum rate, MaxL: maximum level, TMaxL: time to maximum level, AUC: area under the curve.
†
p≤0.001 when compared within each stratification,
‡
p<0.05.