Table 4. Comparison of fXa generation in individuals with a known DVT versus controls.

		N	MaxRPrevalence, %	MaxLPrevalence, %
Whole population	Controls	473	33 (7.5%)	32 (7.3%)
	Cases	426	57 (15.4%)	58 (15.8%)
	Fisher's Exact p-value		0.0017	0.0008
	OR (95% CI)		2.1 (1.3–3.2)	2.2 (1.4–3.4)
Sex/Men	Controls	201	7 (3.5%)	7 (3.5%)
	Cases	172	15 (8.7%)	14 (8.1%)
	Fisher's Exact p-value		0.046	0.070
	OR (95% CI)		2.6 (1.1–6.7)	2.5 (0.97–6.2)
Sex/Women	Controls	272	26 (9.6%)	25 (9.2%)
	Cases	254	42 (16.5%)	43 (16.9%)
	Fisher's Exact p-value		0.019	0.009
	OR (95% CI)		1.9 (1.1–3.2)	2.0 (1.2–3.4)
Females without OC	Controls	90	0 (0%)	1 (1.1%)
	Cases	40	6 (15%)	6 (15%)
	Fisher's Exact p-value		0.0006	0.0034
	OR (95% CI)		undefined	15.7 (1.8–135)
Females with OC	Controls	47	14 (29.8%)	13 (27.6%)
	Cases	30	11 (36.7%)	12 (40.0%)
	Fisher's Exact p-value		0.62	0.32
	OR (95% CI)		1.4 (0.52–3.6)	1.7 (0.66–4.6)
Age≤45 yrs	Controls	223	17 (7.6%)	17 (7.6%)
	Cases	209	31 (14.8%)	32 (15.3%)
	Fisher's Exact p-value		0.021	0.015
	OR (95% CI)		2.1 (1.1–3.9)	2.2 (1.2–4.1)
Age>45 yrs	Controls	250	16 (6.4%)	15 (6.0%)
	Cases	217	26 (12.0%)	26 (12.0%)
	Fisher's Exact p-value		0.051	0.032
	OR (95% CI)		2.0 (1.0–3.8)	2.1 (1.1–5.6)
BMI≤26 kg/m2	Controls	264	12 (4.5%)	10 (3.8%)
	Cases	199	20 (10.1%)	18 (9.0%)
	Fisher's Exact p-value		0.026	0.029
	OR (95% CI)		2.4 (1.1–4.9)	2.5 (1.1–5.6)
BMI>26 kg/m2	Controls	193	20 (10.4%)	21 (10.9%)
	Cases	216	35 (16.2%)	38 (17.6%)
	Fisher's Exact p-value		0.11	0.066
	OR (95% CI)		1.7 (0.93–3.0)	1.8 (0.99–3.1)

OR: odds ratio calculated at the 90% cut off point; BMI: body mass index; OC: oral contraceptives.