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. 2012 Jan 11;7(1):e30068. doi: 10.1371/journal.pone.0030068

Figure 3. Normal presynaptic function of hippocampal CA3-CA1 synapses in Pfn1flx/flx,CaMKII-cre mice.

Figure 3

(A) Basal synaptic transmission, as deduced from input-output curves, was normal in Schaffer-collateral-CA1 synapses of Pfn1flx/flx,CaMKII-cre mice (n = 15 for controls and 10 for mutants). (B) In Pfn1flx/flx,CaMKII-cre mice, no changes were found in paired-pulse ratios (PPR; n = 14 for controls, n = 17 for mutants) at various inter-stimulus intervals (ISI; 10–200 ms). Cumulative curves of amplitudes (C) and inter-event intervals (IEI) of mEPSCs (D) were virtually equal between genotypes (n = 8 in each group). Insets in C and D depict mean values.