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. 2012 Jan 11;7(1):e30068. doi: 10.1371/journal.pone.0030068

Figure 4. Unimpaired synaptic plasticity in the absence of profilin1.

Figure 4

(A) In Pfn1flx/flx,CaMKII-cre mice, no difference was found in LTD induced by low frequency stimulation (1 Hz) of 15 min duration (n = 9 for controls, n = 12 for mutants) when analyzing the last 10 min of the recordings. LTP induced by either a single 100 Hz tetanus of 1 s duration (B) or by theta-burst stimulation (TBS) (C) was also not different between genotypes (1×100 Hz: n = 10 for controls and 8 for mutants; TBS: n = 10 for both groups). ns: not significant.