Table III.
Toxicities (possibly, probably or definitely attributed to protocol therapy)
| Course 1 N=17 |
Courses 2 to 12 N=22 |
|||||
|---|---|---|---|---|---|---|
| Grade |
Grade |
|||||
| 2 | 3 | 4 | 2 | 3 | 4 | |
| Hematologic Toxicities | ||||||
|
| ||||||
| Hemoglobin | 2 | |||||
| Leukocytes | 3 | 2 | 9 | |||
| Neutrophils/granulocytes | 5 | 2 | 5 | |||
| Transfusion:pRBCs | 2 | |||||
|
| ||||||
| Non-Hematologic Toxicities | ||||||
|
| ||||||
| Abdominal pain or cramping | 2 | 3 | ||||
| Anorexia | 1 | |||||
| Bone Pain | 1 | |||||
| Dehydration | 1 | 2 | ||||
| Diarrhea (without colostomy) | 6 | 7 | ||||
| Febrile neutropenia | 2 | |||||
| Hyperkalemia | 1 | |||||
| Hypokalemia | 4 | 1 | 2 | |||
| Hyponatremia | 2 | |||||
| Hypophosphatemia | 1 | |||||
| Nausea | 5 | 1 | ||||
| Stomatitis/pharyngitis (oral pharyngeal mucositis) | 1 | |||||
| Vomiting | 5 | |||||