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. Author manuscript; available in PMC: 2013 Feb 25.
Published in final edited form as: Toxicol Lett. 2011 Nov 30;209(1):58–66. doi: 10.1016/j.toxlet.2011.11.021

Fig. 3. Measurement of (+)-anti-trans-B[a]PDE-dGuo in H358 cells after chemical inhibition.

Fig. 3

H358 cells were treated with 2 μM (−)-B[a]P-7,8-dihydrodiol for 24 h with or without 1 mM probenecid for 24 h and/or 10 nM TCDD for 24 h. (+)-anti-trans-B[a]PDE-dGuo adducts were measured by LC-SRM/MS and normalized by total DNA. Plots show means and standard deviation, (*) indicates p=0.001 compared to control and (**) indicates p=0.013 compared to control; n = 3 for each treatment.