Table 1.
MRI protocol in retinoblastomaa
| Requirements |
|---|
| Scanner and coils |
| Field strength above 1 T |
| 1.5-T system combined with one or two small surface coils (diameter < 5 cm) |
| 3.0-T system combined with multichannel head coil |
| Sequences (minimum requirements) |
| Orbits |
| Transaxial T2-W (slice thickness ≤ 2 mm) |
| Optional: Transaxial CISS (Siemens) / FIESTA (GE) / DRIVE (Philips) |
| Eye(s) and optic nerve(s) |
| In-plane pixel size < 0.5 × 0.5 mm; slice thickness ≤ 2 mm |
| Unilateral disease (or bilateral disease with only one eye strongly affected) |
| Precontrast T1-W; at least one plane: transaxial or sagittal oblique |
| T2-W; at least one plane: transaxial or sagittal oblique |
| Postcontrast T1-W, no FS; transaxial and sagittal oblique |
| Bilateral disease (both eyes strongly affected) |
| Precontrast T1-W (transaxial) |
| T2-W (transaxial) |
| Postcontrast T1-W, no FS; sagittal oblique of both eyes and transaxial |
| Brain |
| Transaxial T2-W (slice thickness ≤ 4 mm) |
| Postcontrast T1-W (2D SE with slice thickness ≤ 3 mm or 3D GRE ≤ 1 mm) |
FS fat-saturation, SE spin-echo, GRE gradient-echo
a Consensus among members of the European Retinoblastoma Imaging Collaboration (ERIC)