Figure 2.
Relationship of serum Parvovirus B19 levels to leukemia DNA methylation class. DNA methylation class determined by recursively-partitioned mixture modeling is shown on the left—six subtypes of leukemia are shown with each subclass in proportionate size to the numbers of leukemia samples within each. The right part consists of box and whisker plots for IgG levels in each class. Controlling for immunophenotype and age, Parvovirus B19 IgG levels were associated with DNA methylation class (p = 0.02) but not IgM (p = 0.92).