Table 1. Studies of chemotherapy followed by radiotherapy vs radiotherapy alone.
Author N° patients | Treatment | Mean survival (months) | Overall 5-year survival |
Dillman10 N: 155 |
•Cisplatin-Vinblastine + RT | 13.8* | 19%* |
•RT | 9.7 | 7% | |
Sause11 N: 458 |
•Cisplatin-Vinblastine + RT | 13.2* | 8%* |
•Cisplatin-Vinblastine +hyperfractionated RT | 12 | 6% | |
•RT | 11.4 | 5% | |
Le Chevalier12,13 N: 353 |
•Cisplatin-Vindesine-Cyclophosphamide-Lomustine + RT | 12* | 12%* (3-year data) |
•RT | 10 | 4% |
* Statistically significant difference