Figure 1. Comparison of the in vitro chemosensitivities (T/C ratio, %) of primary lesions and their paired metastatic NSCLC lesions.

P: primary lesions, M: paired metastatic lesions. The cases surrounded with dotted-line frames were diagnosed as being in vitro-sensitive. The P value for each anticancer drug was calculated using the Paired T test. Fig 1. shows a comparison of CD-DST data between each primary lesion and its paired metastatic lesion for each anticancer drug. For GEM, VNR, and TXT, the T/C ratio of the metastatic lesions was significantly higher than that of the primary lesions. In contrast, for CDDP and 5-FU, no significant differences in chemosensitivity were observed.