Table 3.
Mortality by Age at Natural Menopause
| n | Mortality ratea | Age-adjusted hazard ratio (95% CI) | Fully adjusted hazard ratiob(95% CI) | p valuec | |
|---|---|---|---|---|---|
| All-cause mortality (years) | |||||
| <45 | 163 | 72.69 | 0.89 (0.74, 1.07) | 0.88 (0.73, 1.06) | 0.03 |
| 45–49 | 319 | 64.45 | 0.95 (0.82, 1.10) | 0.96 (0.83, 1.12) | |
| 50–54 | 586 | 65.92 | 1.00 | 1.00 | |
| ≥55 | 179 | 66.98 | 1.12 (0.94, 1.34) | 1.13 (0.95, 1.35) | |
| Cardiovascular mortality (years) | |||||
| <45 | 160 | 40.92 | 0.97 (0.76, 1.24) | 0.96 (0.75, 1.23) | 0.17 |
| 45–49 | 316 | 32.92 | 0.93 (0.76, 1.14) | 0.95 (0.77, 1.16) | |
| 50–54 | 576 | 33.92 | 1.00 | 1.00 | |
| ≥55 | 179 | 40.52 | 1.29 (1.02, 1.63) | 1.30 (1.03, 1.65) | |
a
Per 1000 person-years.
b
Adjusts for age, educational attainment, number of pregnancies, age at menarche, smoking, height, weight, and use of estrogen therapy.
c
From test of linear trend for age at natural menopause.