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Acoustic startle and PPI are decreased in BDNF-tg. (A) Startle amplitude in WT and BDNF-tg female littermates during no stimulus trials and following the presentation of a 120-dB stimulus (startle). (B) Percent prepulse inhibition of the acoustic startle response displayed by the same mice after the presentation of 74, 78, 82, 86, and 90 dB prepulse sound stimuli. N = 9 WT, n = 9 BDNF-tg. (*) P < 0.05 and (**) P < 0.005 vs. WT littermates.
