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Active site comparisons between wild-type and mutant PfPMT. A, overlay of the active sites in the AdoCys·pEA (white) and Y19F·pCho (green) complexes. SAH, S-adenosylhomocysteine. B, overlay of the active sites in the AdoCys·pEA (white) and H132A·pCho (purple) complexes.
