TABLE 3.

Kinetic parameters of 5-DMATS for selected substrates

Substrate	Km	kcat	kcat/Km
	mm	s−1	s−1·m−1
l-Tryptophan (1a)	0.034	0.87	25,588
1-Methyl-dl-tryptophan (2a)	0.10	0.059	590
4-Methyl-dl-tryptophan (3a)	0.25	0.29	1160
6-Methyl-dl-tryptophan (4a)	1.0	0.76	760
6-Fluoro-dl-tryptophan (5a)	0.27	0.29	1074
7-Methyl-dl-tryptophan (6a)	0.47	0.40	851
l-Abrine (7a)	0.26	0.40	1538
N-Acetyl-dl-tryptophan (8a)	0.35	0.10	286
l-β-Homotryptophan (9a)	0.97	0.15	155
dl-Indole-3-lactic acid (10a)	0.67	0.43	642
Indole-3-propionic acid (11a)	0.39	0.39	1000
trans-Indole-3-acrylic acid (12a)	0.40	0.14	350
DMAPP	0.076	1.3	17,105