Table 2.
Incidence of Herpes Simplex Virus Type 2 Infection Among Female Partners, by Study Arm and Follow-up Interval
| Follow-up Interval, Variable | Intervention Group | Control Group | Incidence Rate Ratio (95% CI) | P Value |
| 0–12 mo | ||||
| Participants, No. | 351 | 353 | ||
| Incident events, No. | 17 | 26 | ||
| Person-years, No. | 342.5 | 340.0 | ||
| Incidencea | 4.96 | 7.65 | 0.65 (.35–1.20) | .17 |
| 12–24 mo | ||||
| Participants, No. | 310 | 297 | ||
| Incident events, No. | 22 | 13 | ||
| Person-years, No. | 299.0 | 290.5 | ||
| Incidencea | 7.36 | 4.48 | 1.64 (.83–3.26) | .16 |
| 0–24 mob | ||||
| Participants, No. | 8 | 10 | ||
| Incident events, No. | 1 | 2 | ||
| Person-years | 15.0 | 18.0 | ||
| Incidence per 100 person-years | 6.67 | 11.11 | 0.60 (.05–6.62) | .73 |
| Overall | ||||
| Participants, No. | 359 | 363 | ||
| Incident events, No. | 40 | 41 | ||
| Person-years, No. | 656.5 | 648.5 | ||
| Incidencea | 6.09 | 6.32 | 0.96 (.62–1.49) | .87 |
Abbreviation: CI, confidence interval.
a
Defined as the number of infections per 100 person-years.
b
Females with only baseline and year two follow-up samples.