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. 2011 Nov 21;208(12):2477–2488. doi: 10.1084/jem.20111242

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© 2011 Jung et al.

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Figure 2. — Human hematopoietic cell engraftment and immune cell development in humanized mice. (A) Data represent the percentage of human HLA-ABC⁺ or CD3⁺ cells in the peripheral blood of consecutively analyzed mice at the indicated weeks after transplantation of human CD34⁺ cells. Cumulative data (n = 111) were obtained from >10 independent experiments. Horizontal bars indicate the mean. (B) Flow cytometry data show CD4⁺CD3⁺ or CD8⁺CD3⁺ T cells, B cells (CD19⁺), monocytes (CD14⁺), and conventional (CD11c⁺) or plasmacytoid (CD123⁺) DCs in the spleen. Data shown are representative of more than five independent experiments. (C) Flow cytometry data show the individual population of CD14⁺CD15⁻ monocytes and CD14⁻CD15⁺ neutrophils in the peripheral blood. Shown are representative data from one experiment of two mice.