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. Author manuscript; available in PMC: 2012 Jan 12.
Published in final edited form as: Semin Cancer Biol. 2010 Oct 8;20(5):353–359. doi: 10.1016/j.semcancer.2010.10.005

Table 2.

Number of clonal mutations per cancer identified by whole genome sequencing.

Genome Clonal Mutations Non-silent Mutations Reference
Acute Myeloid Leukemia (n=1) 500–1,000 10 [75]
Acute Myeloid Leukemia (n=1) 750 12 [76]
Small cell lung cancer (n=1) 22,910 101 [78]
Melanoma (n=1) 33,345 182 [77]
Breast cancer (n=3) 27,173 ~200 [70]
Non-small cell lung cancer (n=1) 50,675 302 [74]

Normal Human (between generations) 70 <<1 [14]