Table 2.

Chromosome 6 SNPs associated with adolescent/young adult NSHL

SNP	BP*	USC				P	UC				Combined
		Minor allele	MAF (Ca)	MAF (Co)	OR (95% CI)†		MAF (Ca)	MAF (Co)	OR (95% CI)†	P	OR (95% CI)†	P
rs6903608‡	32536263	C	0.48	0.33	1.7 (1.4-2.1)	4.50 × 10−8	0.40	0.32	1.5 (1.2-1.9)	1.43 × 10−3	1.6 (1.4-1.9)	3.52 × 10−10
rs9268542§	32492699	G	0.51	0.38	1.6 (1.3-1.9)	1.37 × 10−5	0.53	0.39	1.8 (1.4-2.4)	5.76 × 10−6	1.6 (1.4-1.9)	5.35 × 10−10
rs9268528‡	32491086	G	0.51	0.38	1.5 (1.3-1.9)	1.78 × 10−5	0.50	0.37	1.8 (1.4-2.3)	1.07 × 10−6	1.6 (1.4-1.9)	1.19 × 10−9
rs204999§	32217957	G	0.16	0.27	0.5 (0.4-0.7)	1.78 × 10−7	0.21	0.28	0.6 (0.4-0.8)	1.60 × 10−3	0.5 (0.4-0.7)	1.44 × 10−9
rs2858870‡	32680229	G	0.06	0.13	0.4 (0.3-0.6)	1.64 × 10−6	0.07	0.13	0.5 (0.3-0.8)	2.35 × 10−3	0.4 (0.3-0.6)	1.69 × 10−8

^*Chromosome location based on National Center for Biotechnology Information Human Genome Build 36 coordinates.

^†OR (95% CI) adjusted for gender and top 10 eigenvectors.

^‡Directly genotyped in cases and controls analyzed at USC; imputed in cases and controls analyzed at UC using the MACH program.

^§Directly genotyped in all case and control samples.