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. 2011 Dec 19;12(12):9440–9462. doi: 10.3390/ijms12129440

Table 2.

List of crystal structures of HDAC8 determined to date.

PDB ID Resolution (Å) Bound Ligand Mutation Metal Ion
1T64 1.90 Trichostatin A - Zn2+
1T67 2.31 M344 - Zn2+
1T69 2.91 SAHA - Zn2+
1VKG 2.20 CRA-19156 - Zn2+
1W22 2.50 NHB - Zn2+
2V5W 2.00 Substrate - Zn2+
2V5X 2.25 V5X - Zn2+
3EW8 1.80 M344 D101L Zn2+
3EWF 2.50 Substrate H143A Zn2+
3EZP 2.65 M344 D101N Zn2+
3EZT 2.85 M344 D101E Zn2+
3F06 2.55 M344 D101A Zn2+
3F07 3.30 APHA - Zn2+
3F0R 2.54 Trichostatin A - Zn2+
3MZ3 3.20 M344 - Co2+
3MZ4 1.85 M344 D101L Mn2+
3MZ6 2.00 M344 D101L Fe2+
3MZ7 1.90 M344 D101L Co2+