Figure 3.

Symmetric and asymmetric divisions of human cardiac stem cells. (A) Daughter cells of symmetrically dividing mCSCs (asterisks) do not express GATA4 (white), whereas one daughter cell of asymmetrically dividing mCSCs (arrows) shows GATA4 (arrowhead). (B and C) Mitotic vCSC (arrows) show uniform (B) and nonuniform (C) distribution of α-adaptin (green), documenting symmetric and asymmetric division, respectively. (D-F) Daughter cells of symmetrically dividing vCSCs (asterisks) do not express Ets1 (D, blue), whereas one daughter cell of asymmetrically dividing vCSCs (arrows) show Ets1 (E, blue; arrowhead) or GATA6 (F, yellow; arrowhead) [2].