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Human cardiac stem cell division and commitment in niches. (A and B) Mitosis (phospho-H3, magenta; arrows) in c-kitPOS cells; α-adaptin (A, white) and Numb (B, yellow) show a uniform (A) and nonuniform (B) localization in the mitotic c-kitPOS cells. (C-F) c-kitPOS cells show in nuclei Nkx2.5 (C, white; arrowheads) and MEF2C (D, magenta; arrowheads) and in the cytoplasm α-SA (E, red; arrow) and α-cardiac actinin (F, red; arrows) [1].
