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TUDCA inhibited dexamethasone-induced apoptosis in thymus. A, Dexamethasone (1 mg/kg) increased staining for activated caspase-3 in thymus. B, Treatment with TUDCA decreased caspase-3 immunoreactivity in dexamethasone-treated rats. C, TUDCA administration alone did not cause increased caspase-3 staining. D, Thymus tissue from naive rats showed little apoptosis.
