Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Oct 31;4:45. doi: 10.1186/1754-6834-4-45

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2011 Baumann et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Cartoon representing the inhibition mechanism of xylan oligosaccharide with different substrates. (A) Xylan oligosaccharide (XOS) inhibition mechanism with para-nitrophenyl-lacoside (pNP-lac) used as the substrate. (B) XOS inhibition mechanism with PASC used as the substrate. In both cases, the activity of cellobiohydrolase I (TrCel7A) was decreased by the presence of XOS. The active site was most likely occupied by unproductively bound XOS, preventing the substrate from entering the active site tunnel. The degree of inhibition is dependent on the ratio of the binding affinities between the substrate and the inhibitor.