Table 3.
Definitions of OA in the cohort studies included in EPOSA
| Cohort | |||||
|---|---|---|---|---|---|
| ActiFE | ProVA† | LASA | Peñagrande | HCS‡ | |
| Self-reported OA | |||||
| Knee | - | Pain or difficulty moving the knees in the last year? Positive if yes for > 1 month. | Do you have OA? If yes: Would you please tell me if you have complaints of the knee? |
- | - |
| Hip | - | Pain or difficulty moving the hips in the last year? Positive if yes for > 1 month. | Do you have OA? If yes: Would you please tell me if you have complaints of the hip? |
- | - |
| Hand | - | Pain or difficulty moving the hands in the last year? Positive if yes for > 1 month. | Do you have OA? If yes: Would you please tell me if you have complaints of the fingers or hand/wrist? |
- | - |
| Non-specific | - | Positive if "yes" on any of the above | Do you have OA? | Have you had pains in the joints or bones? Did you visit a doctor for this problem? Positive if yes on both questions. |
- |
| Clinical OA | |||||
| Knee | - | Judgement by physician based on physical examination and information from medical records | - | - | Told by doctor to have knee OA |
| Hip | - | Judgement by physician based on physical examination and information from medical records | - | - | - |
| Hand | - | Judgement by physician based on physical examination and information from medical records | - | - | Combination of observed Heberdens nodes by trained nurse and self-reported hand pain. |
| Non-specific | Has a doctor ever told you that you have or had OA/arthritis? | Positive if "yes" on any of the above | General practitioners questionnaire: Has your patient been diagnosed with OA? | Diagnosis in general practitioners' records | Positive if "yes" on any of the above |
| Radiographic OA | |||||
| Knee | - | JSN (K&L ≥ 2) + osteophytes | - | - | JSN (K&L ≥ 2) + osteophytes |
| Hip | - | - | - | - | |
| Hand | - | DIP, PIP of digits 2-3, and CMC of digit 1: JSN (K&L ≥ 2) + osteophytes |
- | - | DIP, PIP, CMC of digits 2-5, and IP: JSN (K&L ≥ 2) + osteophytes |
ActiFE: study on Activity and Function in the Elderly in Ulm, ProVA: Progetto Veneto Anziani, LASA: Longitudinal Aging Study Amsterdam, Peñagrande: Ageing in Peñagrande, HCS: Hertfordshire Cohort Study, DIP: distal interphalangeal joint, PIP: proximal interphalangeal joint, CMC: carpo-metacarpal joint, IP: interphalangeal joint, K&L: Kellgren & Lawrence grading.
† In ProVA., all x-rays were taken at the time of the clinic visit, at the same hospital using the same radiographic equipment with standardized procedures, focus to film distance 100 cm, 55 kV, 8 mA/s. Anteroposterior x-ray of the hip, and weight-bearing anteroposterior and lateral x-rays of both extended knees were performed in standing position. Standard posterior-anterior radiographs of both hands with palm flat and fingers straight were performed.
‡ In HCS, weight bearing anterior-posterior and lateral semi-flexed radiographs of both knees were taken at the same hospital using the same radiographic equipment; a standard tube to film distance of 100|cm was used. Radiographs were performed at a median duration of 6|months (interquartile range (IQR) 4.8-7.2) after the clinic visit. Using the same equipment, anterior-posterior hand radiographs were obtained, with the hand placed as flat as possible.