Table 2. Allelic analyses of CD1D and CD1B variants in the CCALD and AMN patients.

SNP (dbSNP31)	gene	MAF	MAF AMN	MAF CCALD	χ2	P value	empirical P valueb	Odds ratio [CI95%]
rs859008	CD1D	0.09	0.14	0.06	5.99	0.018a	0.020	0.36 [0.16 ; 0.84]
rs859009		0.09	0.15	0.06	7.13	0.010a	0.010	0.34 [0.15 ; 0.77]
rs859013		0.09	0.14	0.05	6.9	0.014a	0.016	0.33 [0.14 ; 0.78]
rs422236		0.41	0.42	0.40	0.12	0.73	-	0.92 [0.56 ; 1.50]
rs11583390	CD1B	0.03	0.03	0.03	-	-	-	-
rs16840096		0.11	0.16	0.09	3.22	0.073	0.118	0.51 [0.24 ; 1.08]
rs3176842		0.17	0.17	0.16	0.05	0.82	-	0.93 [0.49 ; 1.78]
rs35841099		0.004	0.01	0	-	-	-	-
rs962879		0.12	0.17	0.09	3.64	0.056	0.106	0.49 [0.23 ; 1.31]
rs62642468		0.03	0.05	0.02	-	-	-	-

^a: The Fisher's exact test was used for SNP with a Minor Allele Frequency (MAF)<0.10.

^b: Permutation-based empirical P value were calculated for SNP showing a trend of association (P value<0.10).