Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jan 12;8(1):e1002286. doi: 10.1371/journal.pcbi.1002286

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Seifert et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

a) Distribution of log-ratios measured for genomic regions in the Array-CGH data set by [103] comparing the genomes of the Arabidopsis thaliana accessions C24 and Col-0. The log-ratio of a genomic region characterizes changes in copy numbers (deletions or amplifications) or sequence deviations of this region in C24 in comparison to Col-0. Unchanged genomic regions between C24 and Col-0 have log-ratios close to zero. Deletions or sequence deviations of genomic regions in C24 have log-ratios much smaller than zero. Amplifications of genomic regions in C24 have log-ratios much greater than zero. b) Distribution of log-ratios of genomic regions (tiles) in the Array-CGH data set covered to at least 75% (45 bp of 60 bp) by candidate regions of deletions or sequence deviations identified in [101] based on Affymetrix array-based resequencing data [100]. The large proportion of highly negative log-ratios indicates that these candidate regions are also present in the Array-CGH data set. Tiles covered by such candidate regions provide a useful resource for evaluating the identification of deletions or sequence deviations in the Array-CGH data set by different methods.

Inline graphic — a) Distribution of log-ratios measured for genomic regions in the Array-CGH data set by [103] comparing the genomes of the Arabidopsis thaliana accessions C24 and Col-0. The log-ratio of a genomic region characterizes changes in copy numbers (deletions or amplifications) or sequence deviations of this region in C24 in comparison to Col-0. Unchanged genomic regions between C24 and Col-0 have log-ratios close to zero. Deletions or sequence deviations of genomic regions in C24 have log-ratios much smaller than zero. Amplifications of genomic regions in C24 have log-ratios much greater than zero. b) Distribution of log-ratios of genomic regions (tiles) in the Array-CGH data set covered to at least 75% (45 bp of 60 bp) by candidate regions of deletions or sequence deviations identified in [101] based on Affymetrix array-based resequencing data [100]. The large proportion of highly negative log-ratios indicates that these candidate regions are also present in the Array-CGH data set. Tiles covered by such candidate regions provide a useful resource for evaluating the identification of deletions or sequence deviations in the Array-CGH data set by different methods.