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. 2012 Jan 12;7(1):e30143. doi: 10.1371/journal.pone.0030143

Figure 2. c-MET helped the survival of breast cancer cells after the treatment of NaBu.

Figure 2

RT-PCR result illustrated that the expression level of MET was higher in MDA-MB-231 cell than in MCF-7 cells (A). The expression level of MET in MDA-MB-231 cells were decreased by the treatment of MET siRNA (B). Silencing MET in MDA-MB-231 cells resulted in a poor survival rate (7%) when the cells were treated by NaBu (C). For MCF-7 cells, while the MET expression was increased obviously by induction of MET activator (D), the cell survival rate were increased significantly with the presence of NaBu in culturing medium (26%)(E). *P<0.05.