Figure 1.
Mitochondrial protein synthesis over a 6-week period in young, middle, and old AL or CR mice. Liver mitochondrial protein was fully turned over in the 6-week period (A). Heart mitochondrial protein synthesis was less than liver and there was no difference because of age or CR (B). Skeletal muscle mitochondrial protein synthesis was less than heart and had a significant effect of age (p ≤ 0.05), but not because of CR (C). Figure insets for heart and skeletal muscle are in units of %/hr. It was not possible to calculate %/hr for liver since proteins were fully turned over. n = 6–8 per group.