. Author manuscript; available in PMC: 2013 Jan 10.

Published in final edited form as: Biochemistry. 2011 Dec 29;51(1):243–256. doi: 10.1021/bi2015508

Table 1.

K_i values of Pnc1 competitive inhibition by nicotinamide analogs. K_i values were determined as described under Experimental Procedures. All reactions were performed at pH 7.5.

Inhibitor	Structure	K_i value (µM)
nicotinic acid		120 ± 19
pyrazinoic acid		6700 ± 1700
nicotinaldehyde		0.94 ± 0.35
benzaldehyde		20600 ± 5700
3-acetylpyridine		316 ± 101