Table I.
Conservation of actomyosin ring components among divergent eukaryotes
| Protein | S. pombe | C. elegans | N. crassa |
| Profilin | Cdc3 (Balasubramanian et al., 1994) | Pfn-1 (Severson et al., 2002) | S.p, C.e. NCU06397* |
| Myosin essential light chain | Cdc4 (McCollum et al., 1995) | ND | S.p. CU06617* |
| Tropomyosin | Cdc8 (Balasubramanian et al., 1992) | Tmy-1 (Ono and Ono, 2004) | S.p. NCU01204*, C.e. NCU01878 |
| F-BAR domain–containing protein | Cdc15 (Fankhauser et al., 1995) | ND | S.p. NCU10905 |
| Formin | Cdc12 (Chang et al., 1997) | Cyk-1 (Severson et al., 2002) | S.p., C.e. NCU01431* (SepA) |
| Myosin type II heavy chain | Myo2 (Kitayama et al., 1997; May et al., 1997) | Nmy-2 (Shelton et al., 1999) | S.p., C.e. NCU00551 |
| Actin | Act1 (Ishiguro and Kobayashi, 1996) | Act-1/3, Act-2, Act-3 (Velarde et al., 2007) | S.p., C.e. NCU04173*, NCU04247* |
| ADF/cofilin | Adf1 (Nakano and Mabuchi, 2006) | Unc-60 (McKim et al., 1994) | S.p., C.e. NCU01587 |
| IQGAP | Rng2 (Eng et al., 1998) | Pes-7 (Skop et al., 2004) | S.p., C.e. NCU03116* (ras-GAP) |
| UCS domain–containing protein | Rng3 (Balasubramanian et al., 1998) | Unc-45 (Kachur et al., 2004) | S.p., C.e. NCU06821* (Cro1) |
| Myosin regulatory light chain | Rlc1 (Le Goff et al., 2000; Naqvi et al., 2000) | Mlc-4 (Shelton et al., 1999) | S.p., C.e. NCU04120* (Calmodulin) |
| Septin | Spn1, Spn2, Spn3, Spn4 (Wu et al., 2003; An et al., 2004) | Unc-59 (Nguyen et al., 2000) | S.p., C.e. NCU08297* (Cdc3), NCU03515* (Cdc10), NCU02464* (septin-1), NCU03795* (Cdc12) |
| F-BAR domain–containing protein | Imp2 (Demeter and Sazer, 1998) | ND | S.p. NCU10905 |
| Alpha actinin | Ain1 (Wu et al., 2001) | Atn-1 (Barstead et al., 1991) | S.p., C.e. NCU06429 |
| Paxilin | Pxl1 (Ge and Balasubramanian, 2008; Pinar et al., 2008) | ND | S.p. NCU09812.3 |
Genes encoding proteins homologous to highly conserved actomyosin ring components in both S. pombe and C. elegans are represented within the N. crassa genome. S. pombe has been included here because many of the proteins involved in cytokinesis are best characterized in this model system. Asterisk indicates annotated genes. If the name given in the annotation differs from the name of the homologous protein, the given name is indicated in parentheses. ND indicates a homologous role in cytokinesis has not been characterized for this protein. S.p., S. pombe homologue; C.e., C. elegans homologue.