Table 2.
Percentage of total body fat calculated from inguinal, retroperitoneal, perirenal, subscapular and epididymal (in male) fat pads per body weight in aP2-agouti transgenic and wild-type mice fed control, high calcium or NFDM diets at 28, 52 and 78 weeks of age. Values are expressed as mean ± SE. Non-matching superscripts denote significant differences between diet groups, p < 0.05.
| Diet | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| control | high calcium | NFDM | ||||||||||||
| Gender | Genotype | Age | mean ± SE | n | mean ± SE | n | mean ± SE | n | ||||||
| female | wild | 28 wk | 6.53 | ± | 2.89 | 4 | 12.10 | ± | 1.57 | 4 | 9.24 | ± | 2.22 | 4 |
| 52 wk | 18.53 | ± | 2.18 | 4 | 14.37 | ± | 1.07 | 4 | 12.16 | ± | 3.07 | 4 | ||
| 78 wk | 19.42 | ± | 1.49 | 3 | 17.84 | ± | 3.73 | 4 | 12.98 | ± | 1.44 | 3 | ||
| all | 14.41 | ± | 2.26 | 11 | 14.77 | ± | 1.44 | 12 | 11.32 | ± | 1.39 | 11 | ||
| transgenic | 28 wk | 19.27 | ± | 1.69 | 4 | 16.90 | ± | 4.72 | 3 | 12.99 | ± | 0.65 | 4 | |
| 52 wk | 19.24 | ± | 4.39 | 4 | 22.13 | ± | 1.15 | 4 | 16.52 | ± | 1.20 | 4 | ||
| 78 wk | 23.07 | ± | 2.94 | 5 | 23.84 | ± | 4.61 | 3 | 18.62 | ± | 3.33 | 4 | ||
| all | 20.72 | ± | 1.76 | 13 | 21.07 | ± | 1.98 | 10 | 16.05 | ± | 1.29 | 12 | ||
| both | 17.83 | ± | 1.53 a | 24 | 17.64 | ± | 1.36 ab | 22 | 13.79 | ± | 1.05 b | 23 | ||
| male | wild | 28 wk | 12.43 | ± | 0.87 | 4 | 12.73 | ± | 0.66 | 4 | 10.08 | ± | 0.75 | 4 |
| 52 wk | 15.33 | ± | 1.84 | 4 | 15.06 | ± | 0.19 | 4 | 13.65 | ± | 0.36 | 4 | ||
| 78 wk | 17.47 | ± | 1.96 a | 4 | 11.46 | ± | 2.05 b | 4 | 13.44 | ± | 1.11 ab | 4 | ||
| all | 15.07 | ± | 1.05 a | 12 | 13.08 | ± | 0.79 ab | 12 | 12.39 | ± | 0.64 b | 12 | ||
| transgenic | 28 wk | 12.54 | ± | 1.11 | 4 | 12.38 | ± | 0.49 | 5 | 12.87 | ± | 0.94 | 4 | |
| 52 wk | 16.67 | ± | 1.25 a | 3 | 12.88 | ± | 1.08 b | 4 | 13.18 | ± | 0.51 b | 4 | ||
| 78 wk | 19.97 | ± | 0.73 | 3 | 13.98 | ± | 4.94 | 3 | 13.56 | ± | 0.92 | 4 | ||
| all | 16.00 | ± | 1.23 a | 10 | 12.94 | ± | 1.13 b | 12 | 13.20 | ± | 0.43 ab | 12 | ||
| both | 15.50 | ± | 0.79 a | 22 | 13.02 | ± | 0.68 ab | 24 | 12.79 | ± | 0.39 b | 24 | ||
| both | wild | 28 wk | 9.48 | ± | 1.79 | 8 | 12.42 | ± | 0.79 | 8 | 9.66 | ± | 1.09 | 8 |
| 52 wk | 16.93 | ± | 1.46 a | 8 | 14.72 | ± | 0.52 ab | 8 | 12.91 | ± | 1.46 b | 8 | ||
| 78 wk | 18.30 | ± | 1.25 a | 7 | 14.62 | ± | 2.30 ab | 8 | 13.24 | ± | 0.84 b | 7 | ||
| all | 14.76 | ± | 1.18 a | 23 | 13.93 | ± | 0.83 ab | 24 | 11.88 | ± | 0.74 b | 23 | ||
| transgenic | 28 wk | 15.90 | ± | 1.60 | 8 | 14.07 | ± | 1.78 | 8 | 12.93 | ± | 0.52 | 8 | |
| 52 wk | 18.14 | ± | 2.42 | 7 | 17.50 | ± | 1.89 | 8 | 14.85 | ± | 0.87 | 8 | ||
| 78 wk | 21.90 | ± | 1.92 | 8 | 18.91 | ± | 3.74 | 6 | 16.09 | ± | 1.86 | 8 | ||
| all | 18.67 | ± | 1.21 a | 23 | 16.64 | ± | 1.38 ab | 22 | 14.63 | ± | 0.73 b | 24 | ||
| both | 28 wk | 12.69 | ± | 1.42 | 16 | 13.24 | ± | 0.96 | 16 | 11.29 | ± | 0.72 | 16 | |
| 52 wk | 17.49 | ± | 1.32 a | 15 | 16.11 | ± | 1.01 ab | 16 | 13.88 | ± | 0.86 b | 16 | ||
| 78 wk | 20.22 | ± | 1.24 a | 15 | 16.47 | ± | 2.07 ab | 14 | 14.76 | ± | 1.09 b | 15 | ||
| all | 16.72 | ± | 0.88 a | 46 | 15.23 | ± | 0.81 ab | 46 | 13.28 | ± | 0.55 b | 47 | ||