Table 6.
Intervention with vitamin D or vitamin D analogues on falls.
| Study | Study design | n | Sex | Mean age (years) | Treatment | Duration | Results |
|---|---|---|---|---|---|---|---|
| CT, controlled trial; F, female; M, male; D3, cholecalciferol; D2, ergocalciferol;Ac, Alfacalcidol /d, daily; wkly, weekly; Ca, calcium; | |||||||
| Graafmans et al. 1996 (142) | CT | 354 | M/F | >70 | 400 IU D3/d (2 yrs) | 7 mths | No effect on falls |
| Sato et al. 1999 (70) | CT | 86 | M/F | 70 | 40 IU Ac/d | 2 yrs | No effect on falls |
| Latham et al. 2002 (136) | CT | 243 | M/F | 79 | 300,000 IU D3 once | 6 mths | No effect on falls |
| Trivedi et al. 2003 (75) | CT | 2686 | M/F | 75 | 100,000 IU D3 quartley | 5 yrs | No effect on falls |
| Sato et al. 2005 (77) | CT | 96 | F | 74 | 1,000 IU D2/d | 2 yrs | 59% reduction in falls and increase in size/number type 2 muscle |
| Law et al. 2006 (78) | OSD | 3717 | M/F | 85 | 1,100 IU D2/d | 10 mths | Noeffect |
| Broe et al. 2007 (143) | CT | 124 | M/F | 89 | 800 IU D2/d | 5 mths | 72% lower fall rate |