. Author manuscript; available in PMC: 2012 Oct 1.

Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2011 Aug 24;91(10):879–884. doi: 10.1002/bdra.22849

Table 2.

Results of heterogeneity testing for the association between folate-related genetic variants and CTDs and LSLs.

LRT for heterogeneity (p-value)
	MTHFR A1298C (1801131)^a 481/168/20^b	MTHFR C677T (1801133) 487/165/18	MTR A2756G (1805087) 473/176/20	MTRR A66G (1801394) 461/183/25	MCP1 A2518G (1024611) 477/172/19	BHMT G742A (3733890) 481/172/17	TCN2 C777G (1801198) 473/165/30	SHMT C1420T (1979277) 479/172/18	NOS3 G894T (1799983) 469/179/19

Inherited genotype	0.83 (0.66)	1.57 (0.46)	1.55 (0.46)	0.73 (0.69)	0.24 (0.89)	1.96 (0.38)	0.08 (0.96)	0.66 (0.72)	0.80 (0.67)
Maternal genotype	0.09 (0.96)	0.40 (0.82)	10.16 (0.01)	1.77 (0.41)	0.19 (0.91)	0.50 (0.78)	0.40 (0.82)	1.69 (0.43)	2.10 (0.35)

dbSNP rs#

Number of triads with genotype data for 3, 2 or 1 member.