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B. pseudomallei AI ΔBPSS1823 is significantly attenuated in a BALB/c mouse model of infection. Intraperitoneal infection of BALB/c mice (n = 6) with 6.2 × 106 CFU B. pseudomallei AI or 2.5 × 106 CFU B. pseudomallei AI ΔBPSS1823 is shown.