Fig. 2.
Differentially regulated genes in the Anopheles midgut upon Plasmodium infection. (A) Total numbers of differentially regulated genes per Plasmodium species and infection stage, grouped according to infection intensity. Light shaded bars, genes showing an expression change higher than 0.7 log2; dark shaded bars, genes showing smaller but significant changes (P ≤ 0.025) across infection stages. (B) Transcriptional profiles of genes for which data are presented in panel A. Eisengrams are divided into three parts: upregulation (yellow) in at least one infection stage (top), downregulation (blue) in at least one infection stage (middle), and upregulation and downregulation in at least one infection stage (bottom). The total numbers of genes in each eisengram and each eisengram part are given. (C) Up- and downregulated fractions of genes belonging to distinct functional classes. Carb., carbohydrate; metab., metabolism; Repl., replication; transcr., transcription; transl., translation.