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Serum IL-12 and IFN-γ levels after B. abortus infection. IRAK-4−/− and IRAK-4+/− mice were infected and blood samples were collected at 1, 3, and 6 weeks postinfection. IL-12 (A) and IFN-γ (B) levels were measured by ELISA. A significant difference in relation to IRAK-4+/− is denoted by an asterisk (P < 0.05).
