. 2011 Nov;79(11):4688–4695. doi: 10.1128/IAI.05289-11

Table 1.

Percentages of CD4⁺ and CD8⁺ T cells producing IFN-γ in IRAK-4^−/− and IRAK-4^+/− mice at the first and third weeks of infection with B. abortus

Week	T-cell type and mouse genotype	% cells producing IFN-γ after stimulation with^a:
Week	T-cell type and mouse genotype	Medium	HKBa	ConA^b
1	CD4⁺
	IRAK-4^+/−	3.49 ± 1.12	17.55 ± 4.56^#	27.98 ± 3.78^#
	IRAK-4^−/−	3.16 ± 0.62	4.58 ± 1.11^#*	14.92 ± 2.17^#*
	CD8⁺
	IRAK-4^+/−	1.91 ± 0.33	10.23 ± 4.25^#	16.50 ± 4.67^#
	IRAK-4^−/−	0.94 ± 0.25	1.59 ± 0.43^#*	8.11 ± 2.53^#*
3	CD4⁺
IRAK-4^+/−	2.68 ± 0.60	7.19 ± 2.39^#	9.43 ± 3.05^#
IRAK-4^−/−	2.67 ± 1.04	6.21 ± 0.75^#	8.37 ± 1.73^#
	CD8⁺
	IRAK-4^+/−	0.58 ± 0.06	3.34 ± 0.94^#	3.91 ± 1.12^#
	IRAK-4^−/−	1.26 ± 0.58	2.79 ± 0.76^#	7.96 ± 1.78^#*

^#, Statistically significant compared to nonstimulated cells. *, Statistically significant compared to IRAK-4^+/− mice.

ConA, concanavalin A.